Details for gene set NCI_SPHINGOSINE 1-PHOSPHATE (S1P) PATHWAY[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	NCI_SPHINGOSINE 1-PHOSPHATE (S1P) PATHWAY
Enrichment Score (ES)	-0.6736295
Normalized Enrichment Score (NES)	-1.5875527
Nominal p-value	0.0
FDR q-value	0.051820636
FWER p-Value	0.521

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	BID	17017 435	228	2.050	0.0370	No
2	BAX	17832	1000	0.840	0.0155	No
3	CYCS	8821	1104	0.771	0.0285	No
4	CTSD	22	1349	0.617	0.0302	No
5	BCAR1	18741	1602	0.499	0.0285	No
6	MAPK8	6459	1918	0.379	0.0206	No
7	BAG4	7431	2307	0.260	0.0059	No
8	PRKCZ	5260	2458	0.222	0.0031	No
9	PAWR	19885 658	2591	0.193	0.0007	No
10	HRAS	4868	2695	0.167	-0.0009	No
11	SLC9A3R2	23089 1544 1514	3066	0.100	-0.0185	No
12	ITGB3	20631	3085	0.098	-0.0171	No
13	VEGFA	22969	3350	0.072	-0.0296	No
14	FADD	17536 8950 4711	3699	0.052	-0.0472	No
15	GNAI1	9024	3815	0.047	-0.0523	No
16	SHC1	9813 9812 5430	3966	0.042	-0.0594	No
17	GNAQ	4786 23909 3685	4162	0.036	-0.0690	No
18	AKT1	8568	4238	0.034	-0.0723	No
19	GNAZ	71	4248	0.034	-0.0719	No
20	BCL2	8651 3928 13864 4435 981 4062 13863 4027	4399	0.030	-0.0793	No
21	FYN	3375 3395 20052	5080	0.020	-0.1156	No
22	SNX15	23993 3761	5228	0.019	-0.1231	No
23	SPHK1	5484 1266 1402	5477	0.016	-0.1361	No
24	SRC	5507	5732	0.014	-0.1495	No
25	IGF1	3352 9156 3409	6416	0.010	-0.1862	No
26	GNAO1	4785 3829	6928	0.008	-0.2136	No
27	PTGS2	5317 9655	7104	0.007	-0.2229	No
28	STAT5B	20222	7328	0.007	-0.2348	No
29	PAK1	9527	7592	0.006	-0.2489	No
30	SHB	10493	7716	0.005	-0.2554	No
31	HIF1A	4850	7749	0.005	-0.2570	No
32	NCK1	9447 5152	7822	0.005	-0.2608	No
33	KDR	16509	8028	0.005	-0.2717	No
34	GRB10	4799	8037	0.005	-0.2721	No
35	PDGFB	22199 2311	8208	0.004	-0.2811	No
36	GNA14	23907	8215	0.004	-0.2814	No
37	RHOA	8624 4409 4410	8262	0.004	-0.2838	No
38	PTPN2	23414	8307	0.004	-0.2861	No
39	GNA12	9023	8598	0.003	-0.3017	No
40	ACP1	4317	9230	0.002	-0.3357	No
41	PTPN11	5326 16391 9660	9360	0.001	-0.3427	No
42	FLT1	3483 16287	9989	-0.000	-0.3766	No
43	IRS1	4925	10289	-0.001	-0.3928	No
44	CDC42	4503 8722 4504 2465	10407	-0.001	-0.3991	No
45	LYN	16281	10463	-0.001	-0.4020	No
46	CRADD	19640	10936	-0.002	-0.4275	No
47	YES1	5930	10960	-0.003	-0.4286	No
48	LRP1	9284	11848	-0.005	-0.4765	No
49	PLCB2	5262	11963	-0.005	-0.4825	No
50	DOK1	17104 1018 1177	12045	-0.006	-0.4867	No
51	EGF	15169	12130	-0.006	-0.4911	No
52	PIK3R1	3170	12501	-0.008	-0.5110	No
53	PLCG1	14753	12673	-0.009	-0.5200	No
54	SOS1	5476	13043	-0.010	-0.5397	No
55	GNAI3	15198	13214	-0.012	-0.5486	No
56	SPHK2	1217 1806 12155	13294	-0.012	-0.5526	No
57	PDGFRB	23539	13448	-0.013	-0.5605	No
58	PIK3CA	9562	13536	-0.014	-0.5649	No
59	ASAH1	3835 3853 8630	13539	-0.014	-0.5647	No
60	TNF	23004	13662	-0.015	-0.5709	No
61	ABL1	2693 4301 2794	14038	-0.020	-0.5907	No
62	PDGFA	5237	14378	-0.026	-0.6084	No
63	GRB7	20673	14467	-0.028	-0.6125	No
64	CBL	19154	14583	-0.031	-0.6180	No
65	FOS	21202	14780	-0.038	-0.6276	No
66	SMPD3	18757	14795	-0.038	-0.6275	No
67	MAP2K2	19933	14885	-0.041	-0.6313	No
68	GNA15	19671	14917	-0.042	-0.6320	No
69	VAV2	5848 2670	14953	-0.044	-0.6328	No
70	JAK2	23893 9197 3706	15078	-0.050	-0.6383	No
71	STAT5A	20664	15080	-0.050	-0.6372	No
72	AIFM1	2558 24161	15083	-0.050	-0.6361	No
73	MAP2K1	19082	15278	-0.061	-0.6451	No
74	MYC	22465 9435	15293	-0.062	-0.6444	No
75	TNFRSF1A	1181 10206	15409	-0.069	-0.6489	No
76	CDH5	18512	15432	-0.071	-0.6484	No
77	FGR	4723	15710	-0.099	-0.6610	No
78	MAP4K4	11241	15790	-0.111	-0.6626	No
79	ITGAV	4931	15885	-0.127	-0.6646	No
80	HCK	14787	15924	-0.131	-0.6635	No
81	RIPK1	5381	15979	-0.143	-0.6630	No
82	TRAF2	14657	16176	-0.186	-0.6692	Yes
83	PTPN1	5325	16237	-0.200	-0.6676	Yes
84	PTPRJ	9664	16260	-0.207	-0.6638	Yes
85	LCK	15746	16281	-0.210	-0.6598	Yes
86	NCK2	9448	16378	-0.238	-0.6593	Yes
87	BIRC3	19247	16564	-0.296	-0.6622	Yes
88	RAC1	16302	16592	-0.304	-0.6563	Yes
89	AKT3	13739 982	16609	-0.309	-0.6497	Yes
90	RASA1	10174	16776	-0.365	-0.6499	Yes
91	CASP8	8694	16802	-0.373	-0.6423	Yes
92	MAP2K4	20405	16842	-0.384	-0.6352	Yes
93	RAF1	17035	16923	-0.414	-0.6296	Yes
94	SGPL1	19757	17016	-0.451	-0.6237	Yes
95	PRKCD	21897	17066	-0.470	-0.6150	Yes
96	MAPK14	23313	17215	-0.531	-0.6102	Yes
97	BAD	24000	17315	-0.582	-0.6016	Yes
98	SGPP1	21039	17338	-0.596	-0.5885	Yes
99	GRB2	20149	17370	-0.613	-0.5754	Yes
100	PRKRA	357	17374	-0.616	-0.5607	Yes
101	MAPK3	6458 11170	17396	-0.634	-0.5466	Yes
102	JUN	15832	17458	-0.677	-0.5336	Yes
103	GNA13	20617	17482	-0.692	-0.5182	Yes
104	SLC9A3R1	11250	17565	-0.739	-0.5048	Yes
105	NFKB1	15160	17596	-0.757	-0.4883	Yes
106	GNA11	3300 3345 19670	17733	-0.859	-0.4749	Yes
107	RELA	23783	17734	-0.859	-0.4543	Yes
108	SMPD1	18145 2658	17930	-1.041	-0.4398	Yes
109	PTEN	5305	18017	-1.128	-0.4173	Yes
110	GAB1	18828	18101	-1.234	-0.3921	Yes
111	STAT1	3936 5524	18114	-1.257	-0.3625	Yes
112	NFKBIA	21065	18148	-1.309	-0.3328	Yes
113	CSK	8805	18193	-1.378	-0.3020	Yes
114	MAP3K1	21348	18282	-1.594	-0.2684	Yes
115	STAT3	5525 9906	18327	-1.720	-0.2294	Yes
116	DNM2	4635 3103	18366	-1.824	-0.1876	Yes
117	BLK	3205 21791	18473	-2.331	-0.1373	Yes
118	CXCR4	13844	18494	-2.475	-0.0788	Yes
119	MAPK1	1642 11167	18573	-3.548	0.0023	Yes